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Person-to-person transmission of Campylobacter is rare, occurring in young children from adults. The fecal-oral mechanism of infection transmission is realized mainly by the alimentary route. Infection occurs when eating infected meat and dairy products without sufficient heat treatment, as well as vegetables and fruits.
The water way of transmission of infection is possible. Cases of infection with campylobacter are known through contact with sick animals, especially if they have diarrhea.
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In pregnant women, transplacental transmission of the infection is possible. All age groups are susceptible to campylobacteriosis, but children under 10 years of age, including newborns, are predominantly ill.
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Persons who have constant (professional) contact with farm animals are at increased risk of actos pills with campylobacter. High susceptibility to campylobacteriosis distinguishes individuals with weakened resistance, immunodeficiency states, severe comorbidities (alcoholism, drug addiction, cardiovascular diseases, diabetes mellitus, malignant neoplasms), as well as after gastrectomy, treatment with immunosuppressants.
Postinfectious immunity is poorly understood. The disease is recorded in the form of sporadic cases, small and less often - epidemic outbreaks.
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The geographic distribution of campylobacteriosis is very wide, it occurs on all continents, which is associated with the intensification of animal husbandry, the increased international trade in animals, feed, animal products, and the growth of urbanization. Pathogenesis and pathological anatomical picture.
Little studied. The pathogen enters the human body through the mouth with infected food and water. The development of variants of the course of the disease is determined by the state of resistance of the microorganism to infection. In persons with normal reactivity of the organism, infection may not be accompanied by clinical manifestations and is limited to a subclinical form with bacterial excretion.
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On average, the duration of actos is from 2 to 10 days. At the same time, even short-term enterocolitis (within 2-3 days) leads to a sharp exhaustion and weakening of patients. Often, pain in the abdomen, general discomfort and malaise persist after the diarrhea stops. The convalescence period lasts from 2 days to 3 weeks. Typically, the gastrointestinal form of campylobacteriosis ends in complete recovery, but relapses may develop.
Children of the first year of actos are especially hard to tolerate dehydration; their clinical picture of the disease resembles cholera. The severe form of the disease is rare, with it the general intoxication is significantly expressed, the body temperature reaches 40 ° C, accompanied by severe chills, sometimes - delirium and confusion. The hemogram may show moderate leukocytosis.
According to the clinical course, the following forms of pioglitazone are distinguished: gastrointestinal, generalized (septic), chronic, subclinical (bacterial excretion).